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Leptospirosis

Leptospirosis

Leptospirosis is a bacterial infection caused by Leptospira interrogans bacterium. This is also known as infectious jaundice, swamp feer and hemorrhagic jaundice . Leptospirosis is more prevalent in tropical areas especially in areas where there are animals or rodents in urban dwellings. This infection spreads through contact with water, food, or soil containing urine from infected animals. It usually does not spread from person to person.

Typical symproms of Leptospirosis include high fever, muscle aches, vomiting and jaundice. The patient might suffer chills and headache. Other symptoms of leptospirosis are diarrhea, abdominal pain and skin rash. Left untreated, leptospirosis can lead to meningitis, kidney failure and liver failure. Since the symptoms are not very specific, this disease is likely to be neglected. A blood test for Leptospira is done to diagnose the infection. This will show increased liver enzymes and WBC count of less than 10,000. A urine analysis will show abnormality. Leptospirosis is treated with antibiotics, such as doxycycline or penicillin.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that surfaces as inflammation and damage to various parts of the body and its tissues. Lupus can affect the joints, skin, heart, lungs, blood vessels, brain and kidneys. Systemic Lupus Erythematosus affects the blood vessels and connective tissues of the skin. Since the body turns against itself, the tissues become inflamed and swollen. Most often, SLE manifests itself with a butterfly-rash and pain in the joints. This disease is more pronounced among persons of Afro-Caribbean and Asian origin. Women are more likely to be afflicted by Systemic Lupus Erythematosus.

A patient suffering from Systemic Lupus Erythematosus experiences painful swelling in the joints, skin rashes, extreme fatigue, fever and infections due to weakened immune system. Scaly sores on the face (discoid rash) and butterfly-shaped rash on the bridge of the nose (malar rash) are also noticed. SLE also leads to serositis - inflammation in the linings of the hear, lungs and abdomen. There may be weight loss, vomiting and diarrhea. SLE can also cause swollen glands and sensitivity to cold. While symptoms of SLE are often noticed in the years of 15 - 45, it can even occur earlier or later.

This disease tends to appear in periodic flare-ups. Often diagnosis of systemic lupus erythematosus takes time. Blood tests are conducted for checking for the presence of antinuclear antibodies (ANA). Chest x-rays and urine analysis are done. Inflammation levels are checked with sedimentation rate (ESR) or C-reactive protein (CRP). While there is no cure for systemic lupus erythematosus, corticosteroids and anti-inflammatory drugs are prescribed to relieve pain and swelling. Immunosuppresants are also used in the treatment of SLE. Physiotherapy is used to give relief to the patient from pain in the joints.